Detalhe da pesquisa
1.
The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis.
Nature
; 592(7853): 296-301, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33731931
2.
Base editors dissect genetic variants in human hematopoietic cells on a large scale.
Trends Immunol
; 44(7): 490-492, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37316391
3.
Hematopoietic and eosinophil-specific LNK(SH2B3) deficiency promote eosinophilia and arterial thrombosis.
Blood
; 2023 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38096361
4.
BRCC3-Mediated NLRP3 Deubiquitylation Promotes Inflammasome Activation and Atherosclerosis in Tet2 Clonal Hematopoiesis.
Circulation
; 148(22): 1764-1777, 2023 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37781816
5.
MICA/B antibody induces macrophage-mediated immunity against acute myeloid leukemia.
Blood
; 139(2): 205-216, 2022 01 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34359073
6.
Oxidized Phospholipids Promote NETosis and Arterial Thrombosis in LNK(SH2B3) Deficiency.
Circulation
; 144(24): 1940-1954, 2021 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34846914
7.
Studying clonal evolution of myeloid malignancies using induced pluripotent stem cells.
Curr Opin Hematol
; 28(1): 50-56, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33264225
8.
Gene Insertion Into Genomic Safe Harbors for Human Gene Therapy.
Mol Ther
; 24(4): 678-84, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26867951
9.
Gene and Cell Therapy for ß-Thalassemia and Sickle Cell Disease with Induced Pluripotent Stem Cells (iPSCs): The Next Frontier.
Adv Exp Med Biol
; 1013: 219-240, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29127683
10.
Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs.
Nature
; 461(7262): 402-6, 2009 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-19693009
11.
A bioinformatic assay for pluripotency in human cells.
Nat Methods
; 8(4): 315-7, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21378979
12.
Targeting SRSF2 mutations in leukemia with RKI-1447: A strategy to impair cellular division and nuclear structure.
iScience
; 27(4): 109443, 2024 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38558935
13.
R-Loop Accumulation in Spliceosome Mutant Leukemias Confers Sensitivity to PARP1 Inhibition by Triggering Transcription-Replication Conflicts.
Cancer Res
; 84(4): 577-597, 2024 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37967363
14.
A method to sequence and quantify DNA integration for monitoring outcome in gene therapy.
Nucleic Acids Res
; 39(11): e72, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21415009
15.
Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis.
Proc Natl Acad Sci U S A
; 107(34): 15163-8, 2010 Aug 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-20699384
16.
Patient-Derived iPSCs Faithfully Represent the Genetic Diversity and Cellular Architecture of Human Acute Myeloid Leukemia.
Blood Cancer Discov
; 4(4): 318-335, 2023 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37067914
17.
Blockade of IL-6 signaling alleviates atherosclerosis in Tet2-deficient clonal hematopoiesis.
Nat Cardiovasc Res
; 2(6): 572-586, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-37539077
18.
Harnessing endogenous miR-181a to segregate transgenic antigen receptor expression in developing versus post-thymic T cells in murine hematopoietic chimeras.
J Clin Invest
; 119(1): 157-68, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19033646
19.
Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation.
Proc Natl Acad Sci U S A
; 106(31): 12759-64, 2009 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-19549847
20.
MDS/AML with del5q: An acquired "laminopathy"?
Cell Stem Cell
; 29(4): 498-499, 2022 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35395184